Acute diarrhoea can sometimes be caused by viral or bacterial infection and ENTEROSGEL is proven to bind and remove the bacterial toxins from such harmful bacteria such as; E.Coli, Shigella, C.difficile – common causes of gastroenteritis.

A 2018 randomised controlled clinical study published in the BMJ Open Gastroenterology, has shown that Enterosgel significantly reduces the duration of acute diarrhoea in adults.

The study recruited 105 patients from ten GP surgeries across England. Patients were randomised to the treatment group which received Enterosgel and oral rehydration solution for 8 days, or the control group which received oral rehydration solution alone. Patients completed a daily diary to record their symptoms and treatment use. The study found that the duration of diarrhoea was significantly shorter in the group of patients receiving Enterosgel® compared to the control group of patients (27 hours vs 39 hours respectively). Enterosgel® was well tolerated and safe with no serious side effects.

Dr Preeti Pandya, a GP from The Village Practice, Thornton medical centre was the chief investigator and helped design the study. She says: “Acute infectious diarrhoea is a common condition especially in young children. NHS guidance suggests that you can usually treat yourself or your child at home by drinking plenty of fluids or taking an oral rehydration solution which can alleviate dehydration, although this has no effect on the duration of diarrhoea. We know that Enterosgel® can adsorb bacterial toxins, so it can help remove the causes of diarrhoea and reduce its duration, and this may especially benefit vulnerable groups of patients, such as children and the elderly.”

The cause of chronic IBS diarrhoea is more complex and multi-factorial and probably includes immune activation, changes to the gut microbiome, increased gut secretion and, in some patients, bile salt malabsorption. The immune proteins released, the bacterial breakdown products of the micro-environment, together with fat molecules and bile acids can all contribute to the development of diarrhoea in these patients. All these molecules are targets for Enterosgel, and research confirms effective adsorption.