[vc_row full_width=”stretch_row” background_position=”right” css=”.vc_custom_1561394394262{background-image: url(https://enteromed.co.uk/wp-content/uploads/2019/06/shutterstock_263170862_.jpg?id=250364) !important;background-position: center !important;background-repeat: no-repeat !important;background-size: cover !important;}”][vc_column][vc_row_inner][vc_column_inner][vc_empty_space height=”62px”][vc_custom_heading text=”HOW DOES ENTEROSGEL WORK?” font_container=”tag:h2|font_size:44px|text_align:center|color:%23ffffff|line_height:53px” google_fonts=”font_family:Raleway%3A100%2C200%2C300%2Cregular%2C500%2C600%2C700%2C800%2C900|font_style:700%20bold%20regular%3A700%3Anormal” css=”.vc_custom_1561378346484{margin-bottom: 20px !important;}”][vc_empty_space height=”92px”][/vc_column_inner][/vc_row_inner][/vc_column][/vc_row][vc_row full_width=”stretch_row” disable_element=”yes” et_uniqid=”et_custom_uniqid_6098e4c98c472″ css=”.vc_custom_1620632786830{background-color: #fbfbfb !important;}” _et_uniqid=”et_custom_uniqid_new_6098e4cb68857″][vc_column][vc_row_inner content_placement=”middle” css=”.vc_custom_1583351562128{padding-top: 30px !important;padding-bottom: 20px !important;}”][vc_column_inner][vc_custom_heading text=”Enterosgel how it works in IBS” font_container=”tag:h3|font_size:26px|text_align:center|color:%2301438f|line_height:32px” google_fonts=”font_family:Raleway%3A100%2C200%2C300%2Cregular%2C500%2C600%2C700%2C800%2C900|font_style:500%20bold%20regular%3A500%3Anormal” css=”.vc_custom_1583351476147{margin-bottom: 20px !important;}”][mpc_divider width=”36″ content_border_css=”border-color:#cd1719;” lines_color=”#cd1719″ margin_divider=”true” margin_css=”margin-bottom:14px;”][vc_column_text]

by Dr Adam Farmer Consultant Gastroenterologist, Royal Stoke University Hospital

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Enterosgel has adsorption capacity towards some toxins and harmful substances in the gut (e.g. endotoxins, enterotoxins)

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Enterosgel physically binds toxic and harmful substances in the gut and expels them in the stool

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This process of elimination of trapped toxins and other harmful substances can be beneficial for treatment of diarrhoea and other health conditions.

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ENTEROSGEL is an oral intestinal adsorbent.

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ENTEROSGEL is based on organic mineral and water.

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ENTEROSGEL is free from preservatives, any additives, gluten, sugar, sweeteners, lactose, fat, flavours, colouring, plant or animal-derived ingredients.

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ENTEROSGEL is completely non-allergenic.

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ENTEROSGEL is suitable for children and adults, including pregnant or breastfeeding women.

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ENTEROSGEL is not a drug, because it is not absorbed by the body and completely expelled with the stool.

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ENTEROSGEL has a unique porous structure consisting of small micropores and a majority of larger mesopores suitable for adsorption of toxins.

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These properties favour ENTEROSGEL’S adsorption of toxins and limit adsorption of lower molecular mass solutes.

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ENTEROSGEL does not remove any bacteria, ENTEROSGEL removes bacterial toxins and other similar harmful molecules.

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Presentation by Dr Carol Howell, Clinical Lead Enterosgel, at the IBS awareness day at the Functional Gut Clinic, London

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A recent study published in the journal Scientific Reports tested ENTEROSGEL’S adsorption or binding capacity for bacterial toxins, bile acids and pharmaceutical drugs.

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Bacterial toxins

Enterosgel was tested for removal of bacterial toxins released from Clostridium difficile, Shigella and E.coli, which can cause inflammation and damage to the mucosal cells lining the colon resulting in diarrhoea. ENTEROSGEL adsorption of these molecules was compared to an activated carbon (Charcodote) which is used orally to treat cases of poisoning. The results showed that ENTEROSGEL has substantial adsorption or binding capacity for these bacterial toxins (see Figure 1).

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Figure 1. Graphs showing remaining concentration of C.difficile toxin A and Shigella toxin after mixing with Enterosgel, Charcodote and positive control (no adsorbent) for 60/120 minutes (mean + sem).

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The adsorption or binding capacity of ENTEROSGEL was also tested for the 4 most common bile acids, the levels of which can be raised in the intestines of patients with IBS. The results showed that ENTEROSGEL also adsorbed these molecules but to a lesser extent. This was calculated as potentially removing up to 10% of the bile acids produced daily, thereby helping patients with excess levels.

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The study tested the adsorption of 2 common drugs; cetirizine (antihistamine) and amitriptyline (antidepressant) and showed that ENTEROSGEL had a much lower rate of adsorption of these drugs than the Charcodote carbon. As most drugs are adsorbed rapidly by the body within 1 hour, this finding suggests that ENTEROSGEL is safe to use in combination with other drug therapies, as long as patients leave at least a 1 hour gap between administration.

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